Protein Purification
XpressBio TRANSIL Membrane Affinity Kit (8 vials)
The Sovicell TRANSIL Membrane Affinity kit enables researchers to measure the interaction of drugs with a membrane. This in vitro assay is designed to measure the distribution coefficient of test compounds between phosphatidylcholine membranes and an aqueous buffer. We refer to this distribution coefficient as membrane affinity.
Hampton Research HR2-995-01/StockOptions Imidazole #01 pH 6.2, 185 ml
HR2-995-01/StockOptions Imidazole #01 pH 6.2, 185 ml. Please note items from this supplier are non-returnable.
Selleck Chemical LLC Selisistat (EX 527) 25mg 49843-98-3 SEN0014196
Selisistat (EX 527, SEN0014196) is a potent and selective SIRT1 inhibitor with IC50 of 38 nM in a cell-free assay, exhibits >200-fold selectivity against SIRT2 and SIRT3. Phase 2. *For Research & Development use only. Product is not intended for drug, household, or human consumption.
Enzo Life Sciences Pepstatin A (synthetic) (25 mg) CAS: 26305-03-3
Protease inhibitor. Alternative Name: Iva-Val-Val-Sta-Ala-Sta, i-Valeryl-L-Val-L-Val-AHMHA-L-Ala-AHMHA. Formula: C34H63N5O9. MW: 685.9. CAS: 26305-03-3. MI: 14: 7147. Purity: ≥98% (HPLC). Sequence: i-Valeryl-L-Val-L-Val-AHMHA-L-Ala-AHMHA. (AHMHA = (3S,4S)-4-Amino-3-hydroxy-6-methyl-heptanoic acid). Appearance: White to off-white solid. Solubility: Soluble in DMSO (10mg/ml), methanol (1mg/ml) or acetic acid. Long Term Storage: -20°C. Use/Stability: Stable for at least 2 years after receipt when stored at -20°C. Handling: Protect from light.
Bon Opus Biosciences Recombinant Human CNOT6 Protein - Source: E. coli
CCR4-NOT transcription complex subunit 6 is produced by our E.coli expression system and the target gene encoding C193-E340 is expressed with a 6His tag at the C-terminus. Accession#Q9ULM6. Formulation: Supplied as a 0.2 um filtered solution of 500mM PBS, 300mM NaCl, 10%Glycerol, pH7.4
Crescent Chemical Co Inc PEPSTATIN A
Pepstatin A Inhibitor of aspartic proteases, e.g. pepsin, renin, cathepsin D (1 - 3) and of retroviral proteases (4 - 7). Size - 5MG Storage Conditions - +2 °C TO +8 °C Catalog Number - 52682.02 CAS 26305-03-3
Cayman Chemical PPIase-ParvulIn InhIbItr 1mg
A cell-permeable inhibitor of the PPIases Pin1 and Pin4 (IC50s = 1.5 and 1.0 µM, respectively), interacting with the PPIase domain; blocks the proliferation of cancer cells that overexpress Pin1 and Pin4 (IC50 range = 2-5 µM), and similarly inhibits wild MEFs but not Pin1-/- MEFs
Apexbio Technology LLC Lysozyme 5mg
Lysozyme (CAS 9001-63-2) is an endogenous enzyme involved in innate immunity classified as EC 3 2 1 17 It hydrolyzes the -1 4-glycosidic bonds in peptidoglycan a critical component of bacterial cell walls leading to cell lysis Owing to this bacteriolytic activity lysozyme is widely utilized in biomedical research for studying microbial cell wall integrity antibacterial mechanisms and innate immune responses It also serves as a model enzyme for investigating protein structure and function
Cayman Chemical PDE4B InhIbItr 10mg
A PDE4B inhibitor (IC50 = 140 nM); selective for PDE4B over a panel of 20 PDE isoforms and a panel of 39 CNS receptors at 10 µM; inhibits the activity of PDE4C1, PDE3B, 5-HT2C, and σ2 receptor by >50% activity at 10 µM; decreases LPS- or Pam3Cys-induced TNF-α production in mouse BMDMs at 1 µM; reduces cocaine self-administration and the progressive ratio breakpoint in mice at 5 mg/kg
Cayman Chemical SGK1 InhIbItr 10mg
An inhibitor of SGK1 and SGK2 (IC50s = 4.8 and 2.8 nM, respectively); selective for SGK1 and SGK2 over SGK3 in the presence of a high concentration of ATP (IC50s = 0.442, 0.924, and 23.3 μM, respectively); only inhibits AMPK by more than 50% in a panel of 60 additional kinases at 1 μM; prevents phosphorylation of GSK3β in U2OS cells (IC50 = 1.4 μM); decreases cell viability in BYL719-insensitive HCC1954 cells when used in combination with BYL719; reduces tumor growth in an HCC1954 mouse xenograft model when administered at 50 mg/kg in combination with BYL719
Hampton Research HR2-933-14/StockOptions Sodium Acetate #14 pH 4.9, 185 ml
HR2-933-14/StockOptions Sodium Acetate #14 pH 4.9, 185 ml. Please note items from this supplier are non-returnable.